
Signal.
Clinical-grade exosome therapy.
Signal is stem cell-derived exosomes, delivered under clinical supervision to restore the cellular signal time erodes. GMP certified. Peer-reviewed. Measurably better skin — in one session.
Your skin knows how to heal. It just lost the signal.
Exosomes are the cellular postal service — nano-scale vesicles that carry proteins, lipids and RNA between cells. As we age, production drops and the messages get quieter. Signal delivers stem cell-derived exosomes back into your dermis. The conversation resumes.

The product is
the exosome.
Signal Exosomes are a clinical-grade biologic, delivered with microneedling by a licensed clinician. Pore size, texture, and glow — measurably better after a single 60-minute session.
Three concentrations. One standard.
All vials are GMP-certified, batch-tested, cold-chain shipped, and single-use.

Signal · 5B
5 billion exosomes
Maintenance protocol. Post-treatment glow support.
Signal · 20B
20 billion exosomes
Standard clinical dose. Microneedling + serum.
Signal · 100B
100 billion exosomes
Advanced protocol. Scar remodeling and biomarker reset.
The proof is in the data.
Peer-reviewed. Clinically measured. Not a filter.

GMP-certified. Peer-reviewed. Proven.
- ◆19 human studies referenced in Signal's clinical dossier.
- ◆0.7% adverse event rate across 21 supervised trials.
- ◆Consistent results across skin type and Fitzpatrick scale.
- ◆Stem cell-derived. Batch-tested. Every vial documented.
Curious what Signal
would do for you?
Glow Up AI is our free companion tool — upload a selfie and it renders a photorealistic preview of your skin after a Signal exosome treatment, based on real clinical outcomes. It's not the product. Signal exosomes are.

Signal is delivered at certified clinics.
A curated global network of medical aesthetic clinics trained on the Signal protocol. Every vial cold-chain shipped, every treatment supervised by a licensed physician.
Maison Dermatologie
Dr. Camille Rousseau
Signal partner since 2024
Nakamura Aesthetic Institute
Dr. Haruki Nakamura
Signal partner since 2024
The Ellis Clinic
Dr. Priya Ellis
Signal partner since 2023
Beverly Skin Lab
Dr. Marcus Chen
Signal partner since 2023
Studio Derma Milano
Dr. Sofia Bianchi
Signal partner since 2025
Nordic Skin Atelier
Dr. Freja Lindqvist
Signal partner since 2025
Are you a clinician? Bring Signal to your practice.
Apply to become a Signal clinic →
Ready to
restore the signal?
Book your Signal exosome treatment at a certified clinic near you.
"Restore the signal. Recalibrate your biology. Prove it."