Flowing translucent ribbons of glowing exosome vesicles
SGL — 001 / Exosome Therapy

Signal.

Clinical-grade exosome therapy.

Signal is stem cell-derived exosomes, delivered under clinical supervision to restore the cellular signal time erodes. GMP certified. Peer-reviewed. Measurably better skin — in one session.

19
Human studies
0.7%
Adverse event rate
21mo
Sustained results
§ 01 — Thesis

Your skin knows how to heal. It just lost the signal.

Exosomes are the cellular postal service — nano-scale vesicles that carry proteins, lipids and RNA between cells. As we age, production drops and the messages get quieter. Signal delivers stem cell-derived exosomes back into your dermis. The conversation resumes.

Signal exosome serum bottles
SGL-001 · LOT 24.09
§ 02 — The product

The product is
the exosome.

Signal Exosomes are a clinical-grade biologic, delivered with microneedling by a licensed clinician. Pore size, texture, and glow — measurably better after a single 60-minute session.

ProtocolMicroneedling + Exosomes
SessionOne. Approximately 60 minutes.
Investment$800 – $2,500
LongevityResults sustained 21 months
SourceStem cell-derived, batch-tested every vial
Find a Signal clinic →
§ 03 — Formulary

Three concentrations. One standard.

All vials are GMP-certified, batch-tested, cold-chain shipped, and single-use.

Signal exosome vials
SGL-05Stem cell-derived

Signal · 5B

5 billion exosomes

Maintenance protocol. Post-treatment glow support.

SGL-20Stem cell-derived

Signal · 20B

20 billion exosomes

Standard clinical dose. Microneedling + serum.

SGL-100Stem cell-derived

Signal · 100B

100 billion exosomes

Advanced protocol. Scar remodeling and biomarker reset.

§ 04 — Evidence

The proof is in the data.

Peer-reviewed. Clinically measured. Not a filter.

41%
Pore reduction
12-week study, n=124
42%
Erythema reduced
Standardized VISIA imaging
21mo
Results sustained
Longitudinal follow-up
Exosome vesicles

GMP-certified. Peer-reviewed. Proven.

  • 19 human studies referenced in Signal's clinical dossier.
  • 0.7% adverse event rate across 21 supervised trials.
  • Consistent results across skin type and Fitzpatrick scale.
  • Stem cell-derived. Batch-tested. Every vial documented.
§ 05 — Companion tool

Curious what Signal
would do for you?

Glow Up AI is our free companion tool — upload a selfie and it renders a photorealistic preview of your skin after a Signal exosome treatment, based on real clinical outcomes. It's not the product. Signal exosomes are.

AI facial mapping preview
SCAN · 47 MARKERS · FREE
§ 06 — Partner clinics

Signal is delivered at certified clinics.

A curated global network of medical aesthetic clinics trained on the Signal protocol. Every vial cold-chain shipped, every treatment supervised by a licensed physician.

Paris, FR

Maison Dermatologie

Dr. Camille Rousseau

Signal partner since 2024

Tokyo, JP

Nakamura Aesthetic Institute

Dr. Haruki Nakamura

Signal partner since 2024

London, UK

The Ellis Clinic

Dr. Priya Ellis

Signal partner since 2023

Los Angeles, US

Beverly Skin Lab

Dr. Marcus Chen

Signal partner since 2023

Milan, IT

Studio Derma Milano

Dr. Sofia Bianchi

Signal partner since 2025

Copenhagen, DK

Nordic Skin Atelier

Dr. Freja Lindqvist

Signal partner since 2025

Are you a clinician? Bring Signal to your practice.

Apply to become a Signal clinic →
§ 07 — Begin

Ready to
restore the signal?

Book your Signal exosome treatment at a certified clinic near you.

"Restore the signal. Recalibrate your biology. Prove it."